The beginning of the First World War complicated the activity of educational institutions. In February 1915, doctor of chemistry, professor Ivan Pavlovich Osipov was elected director of the Kharkov Institute of Technology. In addition to purely educational work, he was forced to take care for issues of additional funding, improvement of the financial situation of employees in connection with the increase in the cost of living, postponement of military conscription of students, etc. A Military-Technical Commission was established at the Kharkov Institute of Technology to resolve defense-related issues. The mechanical laboratory and its workshops were reoriented to the needs of wartime. The institute fulfilled orders for the manufacture of military equipment, in particular, lathes for turning artillery shells.
The events that took place on the fronts of the First World War required the availability of a large number of medicinal drugs, many of which the Russian Empire received from abroad, including Germany. There was an urgent need to establish native production of medicinal substances. In April 1916, in Petrograd, Osipov took part in a meeting on the production of chemical preparations for military needs. Taking into account that many men were mobilized for the army, Osipov, together with like-minded people from the South Russian Society of Technologists, proposed to create a women's higher technical educational institution in Kharkov. In the fall of 1916, the Kharkov Women’s Polytechnic Institute was opened and Osipov became its director.

The Second World War became a serious test for the entire Ukrainian people. Ukrainian scientists also joined the fight against the enemy. Scientists of the Institute of Microbiology and Epidemiology: director of the institute Petro Marusenko, scientific secretary Petro Vizir and about twenty employees joined the ranks of the active army. Scientists who remained in the rear took part in the creation of defense structures, and at workplaces they gave all their strength to meet the needs of the front. The front was approaching, and the Academy of Sciences of Ukraine began to be evacuated to the deep rear. Scientists of the Institute of Microbiology left Kyiv on July 3, 1941 and arrived in Ufa after a long, tiring journey.
Despite the harsh climatic and household conditions, scientific work began to improve. Microbiologists proposed a staphylococcal bacteriophage for combating infections after wounds, which were successfully used in clinics and hospitals in Ufa and other settlements of Bashkiria. In early winter 1941 a significant part of the harvest remained under the snow. According to the instructions of our microbiologists, numerous samples of grain that overwintered under the snow were analyzed. In this way, thousands of poods of bread, which turned out to be of good quality, were saved, and stocks dangerous for use in food were destroyed, which prevented the spread of septic angina and saved the lives of many people.

Ukraine needs not only fuel, energy, but also an ecological future for our nation. The role of biogas plants in the economy of Ukraine is significant, as it provides opportunities for ecological energy production and energy balance during the Russian-Ukrainian war.
Research into the role of biogas plants and their distribution will solve the problems of methane air pollution, the energy crisis in Ukraine and safe energy production. Currently, Ukraine has about 70 biogas plants, including those currently under construction. The latter figure can be obtained as a result of growing energy crops on 5 million hectares of abandoned land.
Biogas production from solid household waste is one of the most promising areas, because approximately 10 million tons of waste are generated in Ukraine every year. Ukraine has a significant potential of bioresources for biogas production, the use of which will allow satisfying 4-7% of the country's annual energy needs.
Currently, the country is in a very difficult state, due to aggression from the Russian Federation. The potential of biogas plants can be used to restore the energy and fuel system of Ukraine. Providing enterprises and ordinary households with gas obtained from waste will give Ukraine an additional economic advantage.
In addition, biogas production has a positive impact on the environment, namely: it does not harm the environment; the amount of garbage used as raw material will be reduced, etc. In general, biogas production will improve the state of the economy, ecology, and energy sector of Ukraine.